Arsenal will be without Noni Madueke for Saturday’s FA Cup quarter-final against Southampton, with manager Mikel Arteta confirming the attacker has not recovered in time after suffering a knee problem during England duty. The setback adds to an already crowded injury picture at Arsenal, though there is some relief in the possibility that Martin Odegaard and Jurrien Timber could return for the tie.
Madueke picked up the issue during England’s friendly against Uruguay and missed the subsequent game against Japan. Arteta said the problem is not as serious as the knee injury that previously sidelined him for six weeks, but it is still enough to rule him out of this weekend’s cup test.

A squad still carrying too many absences
The bigger issue for Arsenal is scale. Madueke was one of a long list of players who either withdrew from international duty or stayed away because of injuries or fitness management. Reuters reported earlier in the week that Arsenal had already seen multiple senior players return early from national team camps, including Bukayo Saka, Declan Rice, William Saliba, Gabriel Magalhaes, Leandro Trossard, Eberechi Eze and Timber, while Odegaard remained in London recovering from a knee problem.
The boost Arteta is waiting for
That is why the possible return of Odegaard and Timber matters. Arsenal are not in a position to rotate casually. Arteta said he wants to field the strongest lineup possible as the club tries to respond to last month’s League Cup final defeat to Manchester City and push on in every competition still open to them.

Why the Southampton game matters
This is more than just a routine cup tie. Arsenal are only a few games away from Wembley and know the FA Cup offers them another major route to silverware while they continue their Premier League title push. That gives the Southampton match extra weight, especially at a moment when squad availability is shaping almost every selection decision.
What comes next
For now, Arsenal’s team news carries both damage and encouragement. Madueke is out, but the possible return of Odegaard and Timber gives Arteta at least a chance to stabilise the squad before a critical stretch. The final picture may stay unclear until matchday, but the message from Arteta was simple: Arsenal have to be as strong as possible, because the margin for error is now small.
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